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Glen Research 10-1001说明书

更新时间：2018-08-15 点击次数：1714

美国GRC公司：Glen Research Corp 创建于1987年，专注于为DNA和RNA寡核苷酸的化学合成，修饰，标记和纯化提供zui广泛的亚磷酰胺和固体支持物，现已有近三十年的历史，在低聚核苷酸及修饰、改性领域一直处于地位。

结构研究

以下产品用于研究当关键结构元件改变时对寡核苷酸活性的影响。7-脱氮嘌呤单体缺乏对氢键合至关重要的基团。7-Deaza-8-aza-A和7-deaza-8-aza-G（PPG）单体是A和G的异构体，并且具有相似的电子密度。它们在寡核苷酸中的存在相对于A和G略微稳定。与G不同，PPG不会导致聚集，并且可以容易地制备和分离富含G的寡核苷酸。在5'-末端具有PPG的5'-荧光素寡核苷酸比等同的G寡核苷酸淬灭得少得多。作为胸苷的嘌呤类似物，7-脱氮-2'-脱氧黄嘌呤核苷（7-deaza-dX）有望对三链体的DNA结构产生有趣的影响。7-Deaza-dX还与2,4-二氨基嘧啶核苷类似物形成非标准碱基对。标准核碱基具有未共享的电子对，其突出到双链DNA的小沟中。与DNA，聚合酶，逆转录酶，限制酶等相互作用的酶可以使用氢键供体基团与小沟中的氢键受体接触。3-Deaza-2'-deoxyadenosine非常有趣，因为它保持了常规Watson-Crick氢与T键合的能力，但缺乏通常由N3提供的3-位的电子对。

GlenResearch 目录号：10-1001-xx

7-Deaza-dA-CE Phosphoramidite
描述：7- Deaza -dA-CE亚磷酰胺

5'-二甲氧基三苯甲基-N-苯甲酰基-7-脱氮-2'-脱氧腺苷，3' - [（2-氰基乙基） - （N，N-二异丙基）] - 亚磷酰胺

分子式：C _4 8 H _5 3 N ₆ O ₇ P.

MW：856.96

FW：312.22

稀释剂：无水乙腈

耦合：合成器制造商推荐的标准方法无需更改。

去保护：合成器制造商推荐的标准方法无需更改。

储存：冷藏，高2-8°C，干燥

溶液中的稳定性：类似于dA，C，G，T-CE亚磷酰胺

10-1001-95

50µm

10-1001-90

100µm

10-1001-02

0.25g

EXTINCTION DATA

Item	Nucleoside	λMax-1	Emax-1	λMax-2	Emax-2	E260
		(nm)	(ml/µmole)	nm	(ml/µmole)	(ml/µmole)
10-1001	7-deaza-dA	270	11.3			9.4

DILUTION/COUPLING DATA

下表显示了包装尺寸数据，以及基于正常灌注程序的溶液，稀释液和近似偶联。请与各种合成器链接以获取更详细的使用信息。

ABI 392/394
Cat.No.	Pack Size	Grams/ Pack	0.1M Dil. (mL)	LV40	LV200	40nm	0.2µm	1µm	10µm
Cat.No.	Pack Size	Grams/ Pack	0.1M Dil. (mL)	Approximate Number of Additions
10-1001-02	0.25grams	.25grams	2.92	84	50.4	31.5	22.91	16.8	4.2
10-1001-90	100µmoles	.086grams	1	20	12	7.5	5.45	4	1
10-1001-95	50µmoles	.043grams	.5	3.33	2	1.25	.91	.67	.17
Expedite
Cat.No.	Pack Size	Grams/ Pack	Dilution (mL)	Molarity	50nm	0.2µm	1µm	15µm
Cat.No.	Pack Size	Grams/ Pack	Dilution (mL)	Approximate Number of Additions
10-1001-02	0.25grams	.25grams	4.35	.07	80.6	50.38	36.64	5.04
10-1001-90	100µmoles	.086grams	1.5	.07	23.6	14.75	10.73	1.48
10-1001-95	50µmoles	.043grams	.75	.07	8.6	5.38	3.91	.54

货号	品名	规格	目录价	品牌
10-0001-02	dA-5'-CE Phosphoramidite	0.25grams	1275	glen research
10-0001-05	dA-5'-CE Phosphoramidite	0.5grams	2550	glen research
10-0001-10	dA-5'-CE Phosphoramidite	1.0gram	5100	glen research
10-0101-02	dC-5'-CE Phosphoramidite	0.25grams	1275	glen research
10-0101-05	dC-5'-CE Phosphoramidite	0.5grams	2550	glen research
10-0101-10	dC-5'-CE Phosphoramidite	1.0gram	5100	glen research
10-0301-02	dT-5'-CE Phosphoramidite	0.25grams	1275	glen research
10-0301-05	dT-5'-CE Phosphoramidite	0.5grams	2550	glen research
10-0301-10	dT-5'-CE Phosphoramidite	1.0gram	5100	glen research
10-1000-02	dA-CE Phosphoramidite	0.25grams	212.5	glen research
10-1000-02M	dA-CE Phosphoramidite	0.25grams	212.5	glen research
10-1000-05	dA-CE Phosphoramidite	0.5grams	425	glen research
10-1000-05M	dA-CE Phosphoramidite	0.5grams	425	glen research
10-1000-10	dA-CE Phosphoramidite	1.0gram	850	glen research
10-1000-10M	dA-CE Phosphoramidite	1.0gram	850	glen research
10-1000-1C	dA-CE Phosphoramidite	1.0gram	850	glen research
10-1000-1S	dA-CE Phosphoramidite	10.0grams	8500	glen research
10-1000-20	dA-CE Phosphoramidite	2.0grams	1700	glen research
10-1000-2C	dA-CE Phosphoramidite	2.0grams	1700	glen research
10-1000-40	dA-CE Phosphoramidite	4.0grams	3400	glen research
10-1000-50	dA-CE Phosphoramidite	5.0grams	4250	glen research
10-1000-5S	dA-CE Phosphoramidite	5.0grams	4250	glen research
10-1000-C2	dA-CE Phosphoramidite	0.25grams	212.5	glen research
10-1000-C5	dA-CE Phosphoramidite	0.5grams	425	glen research
10-1001-02	7-Deaza-dA-CE Phosphoramidite	0.25grams	16575	glen research
10-1001-90	7-Deaza-dA-CE Phosphoramidite	100µmoles	6035	glen research
10-1001-95	7-Deaza-dA-CE Phosphoramidite	50µmoles	3017.5	glen research
10-1002-02	dA+dG-CE Phosphoramidite	0.25grams	680	glen research
10-1003-02	N6-Me-dA-CE Phosphoramidite	0.25grams	8415	glen research
10-1003-90	N6-Me-dA-CE Phosphoramidite	100µmoles	2762.5	glen research
10-1004-02	3'-dA-CE Phosphoramidite	0.25grams	16575	glen research
10-1004-90	3'-dA-CE Phosphoramidite	100µmoles	6035	glen research
10-1004-95	3'-dA-CE Phosphoramidite	50µmoles	3017.5	glen research
10-1006-02	Etheno-dA-CE Phosphoramidite	0.25grams	4335	glen research
10-1006-90	Etheno-dA-CE Phosphoramidite	100µmoles	1785	glen research
10-1007-02	8-Br-dA-CE Phosphoramidite	0.25grams	5015	glen research
10-1007-90	8-Br-dA-CE Phosphoramidite	100µmoles	1955	glen research
10-1008-02	8-oxo-dA-CE Phosphoramidite	0.25grams	6035	glen research
10-1008-90	8-oxo-dA-CE Phosphoramidite	100µmoles	2295	glen research
10-1010-02	dC-CE Phosphoramidite	0.25grams	212.5	glen research
10-1010-02M	dC-CE Phosphoramidite	0.25grams	212.5	glen research
10-1010-05	dC-CE Phosphoramidite	0.5grams	425	glen research
10-1010-05M	dC-CE Phosphoramidite	0.5grams	425	glen research
10-1010-10	dC-CE Phosphoramidite	1.0gram	850	glen research
10-1010-10M	dC-CE Phosphoramidite	1.0gram	850	glen research
10-1010-1C	dC-CE Phosphoramidite	1.0gram	850	glen research
10-1010-1S	dC-CE Phosphoramidite	10.0grams	8500	glen research
10-1010-20	dC-CE Phosphoramidite	2.0grams	1700	glen research
10-1010-2C	dC-CE Phosphoramidite	2.0grams	1700	glen research
10-1010-40	dC-CE Phosphoramidite	4.0grams	3400	glen research
10-1010-50	dC-CE Phosphoramidite	5.0grams	4250	glen research
10-1010-5S	dC-CE Phosphoramidite	5.0grams	4250	glen research
10-1010-C2	dC-CE Phosphoramidite	0.25grams	212.5	glen research
10-1010-C5	dC-CE Phosphoramidite	0.5grams	425	glen research
10-1013-02	dC+dT-CE Phosphoramidite	0.25grams	680	glen research
10-1014-02	pdC-CE Phosphoramidite	0.25grams	4165	glen research
10-1014-05	pdC-CE Phosphoramidite	0.5grams	8330	glen research
10-1014-90	pdC-CE Phosphoramidite	100µmoles	1445	glen research
10-1015-02	Ac-dC-CE Phosphoramidite	0.25grams	212.5	glen research
10-1015-02M	Ac-dC-CE Phosphoramidite	0.25grams	212.5	glen research
10-1015-05	Ac-dC-CE Phosphoramidite	0.5grams	425	glen research
10-1015-05M	Ac-dC-CE Phosphoramidite	0.5grams	425	glen research
10-1015-10	Ac-dC-CE Phosphoramidite	1.0gram	850	glen research
10-1015-10M	Ac-dC-CE Phosphoramidite	1.0gram	850	glen research
10-1015-1C	Ac-dC-CE Phosphoramidite	1.0gram	850	glen research
10-1015-1S	Ac-dC-CE Phosphoramidite	10.0grams	8500	glen research
10-1015-20	Ac-dC-CE Phosphoramidite	2.0grams	1700	glen research
10-1015-2C	Ac-dC-CE Phosphoramidite	2.0grams	1700	glen research
10-1015-40	Ac-dC-CE Phosphoramidite	4.0grams	3400	glen research
10-1015-50	Ac-dC-CE Phosphoramidite	5.0grams	4250	glen research
10-1015-5S	Ac-dC-CE Phosphoramidite	5.0grams	4250	glen research
10-1015-C2	Ac-dC-CE Phosphoramidite	0.25grams	212.5	glen research
10-1015-C5	Ac-dC-CE Phosphoramidite	0.5grams	425	glen research
10-1016-02	TMP-F-dU-CE Phosphoramidite	0.25grams	8415	glen research
10-1016-90	TMP-F-dU-CE Phosphoramidite	100µmoles	3315	glen research
10-1017-02	Pyrrolo-dC-CE Phosphoramidite	0.25grams	11475	glen research
10-1017-90	Pyrrolo-dC-CE Phosphoramidite	100µmoles	3740	glen research
10-1017-95	Pyrrolo-dC-CE Phosphoramidite	50µmoles	1870	glen research
10-1018-02	5-Me-dC Brancher Phosphoramidite	0.25grams	8585	glen research
10-1018-90	5-Me-dC Brancher Phosphoramidite	100µmoles	3485	glen research
10-1019-02	Amino-Modifier C6 dC	0.25grams	7650	glen research
10-1019-90	Amino-Modifier C6 dC	100µmoles	3825	glen research
10-1020-02	dG-CE Phosphoramidite	0.25grams	212.5	glen research
10-1020-02M	dG-CE Phosphoramidite	0.25grams	212.5	glen research
10-1020-05	dG-CE Phosphoramidite	0.5grams	425	glen research
10-1020-05M	dG-CE Phosphoramidite	0.5grams	425	glen research
10-1020-10	dG-CE Phosphoramidite	1.0gram	850	glen research
10-1020-10M	dG-CE Phosphoramidite	1.0gram	850	glen research
10-1020-1C	dG-CE Phosphoramidite	1.0gram	850	glen research
10-1020-1S	dG-CE Phosphoramidite	10.0grams	8500	glen research
10-1020-20	dG-CE Phosphoramidite	2.0grams	1700	glen research
10-1020-2C	dG-CE Phosphoramidite	2.0grams	1700	glen research
10-1020-40	dG-CE Phosphoramidite	4.0grams	3400	glen research
10-1020-50	dG-CE Phosphoramidite	5.0grams	4250	glen research
10-1020-5S	dG-CE Phosphoramidite	5.0grams	4250	glen research
10-1020-C2	dG-CE Phosphoramidite	0.25grams	212.5	glen research
10-1020-C5	dG-CE Phosphoramidite	0.5grams	425	glen research
10-1021-02	7-deaza-dG-CE Phosphoramidite	0.25grams	16575	glen research
10-1021-90	7-deaza-dG-CE Phosphoramidite	100µmoles	6035	glen research
10-1021-95	7-deaza-dG-CE Phosphoramidite	50µmoles	3017.5	glen research
10-1023	dA+dC+dG+dT-CE Phosphoramidite Mix	1.0gram	680	glen research
10-1027-02	8-Br-dG-CE Phosphoramidite	0.25grams	4335	glen research
10-1027-90	8-Br-dG-CE Phosphoramidite	100µmoles	1785	glen research
10-1028-02	8-oxo-dG-CE Phosphoramidite	0.25grams	16575	glen research
10-1028-90	8-oxo-dG-CE Phosphoramidite	100µmoles	6035	glen research
10-1028-95	8-oxo-dG-CE Phosphoramidite	50µmoles	3017.5	glen research
10-1029-02	dmf-dG-CE Phosphoramidite	0.25grams	212.5	glen research
10-1029-02M	dmf-dG-CE Phosphoramidite	0.25grams	212.5	glen research
10-1029-05	dmf-dG-CE Phosphoramidite	0.5grams	425	glen research
10-1029-05M	dmf-dG-CE Phosphoramidite	0.5grams	425	glen research
10-1029-10	dmf-dG-CE Phosphoramidite	1.0gram	850	glen research
10-1029-10M	dmf-dG-CE Phosphoramidite	1.0gram	850	glen research
10-1029-1C	dmf-dG-CE Phosphoramidite	1.0gram	850	glen research
10-1029-1S	dmf-dG-CE Phosphoramidite	10.0grams	8500	glen research
10-1029-20	dmf-dG-CE Phosphoramidite	2.0grams	1700	glen research
10-1029-2C	dmf-dG-CE Phosphoramidite	2.0grams	1700	glen research
10-1029-40	dmf-dG-CE Phosphoramidite	4.0grams	3400	glen research
10-1029-50	dmf-dG-CE Phosphoramidite	5.0grams	4250	glen research
10-1029-5S	dmf-dG-CE Phosphoramidite	5.0grams	4250	glen research
10-1029-C2	dmf-dG-CE Phosphoramidite	0.25grams	212.5	glen research
10-1029-C5	dmf-dG-CE Phosphoramidite	0.5grams	425	glen research
10-1030-02	dT-CE Phosphoramidite	0.25grams	212.5	glen research
10-1030-02M	dT-CE Phosphoramidite	0.25grams	212.5	glen research
10-1030-05	dT-CE Phosphoramidite	0.5grams	425	glen research
10-1030-05M	dT-CE Phosphoramidite	0.5grams	425	glen research
10-1030-10	dT-CE Phosphoramidite	1.0gram	850	glen research
10-1030-10M	dT-CE Phosphoramidite	1.0gram	850	glen research
10-1030-1C	dT-CE Phosphoramidite	1.0gram	850	glen research
10-1030-1S	dT-CE Phosphoramidite	10.0grams	8500	glen research
10-1030-20	dT-CE Phosphoramidite	2.0grams	1700	glen research
10-1030-2C	dT-CE Phosphoramidite	2.0grams	1700	glen research
10-1030-40	dT-CE Phosphoramidite	4.0grams	3400	glen research
10-1030-50	dT-CE Phosphoramidite	5.0grams	4250	glen research
10-1030-5S	dT-CE Phosphoramidite	5.0grams	4250	glen research
10-1030-C2	dT-CE Phosphoramidite	0.25grams	212.5	glen research
10-1030-C5	dT-CE Phosphoramidite	0.5grams	425	glen research
10-1031-02	5'-OMe-dT-CE Phosphoramidite	0.25grams	6035	glen research
10-1031-90	5'-OMe-dT-CE Phosphoramidite	100µmoles	2295	glen research
10-1032-02	O4-Me-dT-CE Phosphoramidite	0.25grams	6035	glen research
10-1032-90	O4-Me-dT-CE Phosphoramidite	100µmoles	2295	glen research
10-1034-02	4-Thio-dT-CE Phosphoramidite	0.25grams	11475	glen research
10-1034-90	4-Thio-dT-CE Phosphoramidite	100µmoles	5015	glen research
10-1034-95	4-Thio-dT-CE Phosphoramidite	50µmoles	2805	glen research
10-1035-02	Carboxy-dT	0.25grams	6120	glen research
10-1035-90	Carboxy-dT	100µmoles	3060	glen research
10-1036-02	2-Thio-dT-CE Phosphoramidite	0.25grams	11475	glen research
10-1036-90	2-Thio-dT-CE Phosphoramidite	100µmoles	5015	glen research
10-1036-95	2-Thio-dT-CE Phosphoramidite	50µmoles	2805	glen research
10-1037-02	Amino-Modifier C2 dT	0.25grams	6120	glen research
10-1037-05	Amino-Modifier C2 dT	0.5grams	12240	glen research
10-1037-90	Amino-Modifier C2 dT	100µmoles	3060	glen research
10-1038-02	Biotin-dT	0.25grams	10625	glen research
10-1038-90	Biotin-dT	100µmoles	5525	glen research
10-1038-95	Biotin-dT	50µmoles	2847.5	glen research
10-1039-02	Amino-Modifier C6 dT	0.25grams	6120	glen research
10-1039-05	Amino-Modifier C6 dT	0.5grams	12240	glen research
10-1039-90	Amino-Modifier C6 dT	100µmoles	3060	glen research
10-1040-02	dI-CE Phosphoramidite	0.25grams	2040	glen research
10-1040-90	dI-CE Phosphoramidite	100µmoles	850	glen research
10-1041-02	2'-DeoxyNebularine-CE Phosphoramidite (Purine)	0.25grams	4335	glen research
10-1041-90	2'-DeoxyNebularine-CE Phosphoramidite (Purine)	100µmoles	1785	glen research
10-1042-02	O6-Phenyl-dI-CE Phosphoramidite	0.25grams	6035	glen research
10-1042-90	O6-Phenyl-dI-CE Phosphoramidite	100µmoles	2295	glen research
10-1044-02	5-Nitroindole-CE Phosphoramidite	0.25grams	5525	glen research
10-1044-90	5-Nitroindole-CE Phosphoramidite	100µmoles	2125	glen research
10-1046-02	2-Aminopurine-CE Phosphoramidite	0.25grams	6035	glen research
10-1046-90	2-Aminopurine-CE Phosphoramidite	100µmoles	2295	glen research
10-1047-02	dP-CE Phosphoramidite	0.25grams	10115	glen research
10-1047-90	dP-CE Phosphoramidite	100µmoles	3315	glen research
10-1048-02	dK-CE Phosphoramidite	0.25grams	10115	glen research
10-1048-90	dK-CE Phosphoramidite	100µmoles	3315	glen research
10-1049-02	dP+dK-CE Phosphoramidite	0.25grams	10115	glen research
10-1049-90	dP+dK-CE Phosphoramidite	100µmoles	3315	glen research
10-1050-02	dU-CE Phosphoramidite	0.25grams	1700	glen research
10-1050-90	dU-CE Phosphoramidite	100µmoles	595	glen research
10-1051-02	O4-Triazolyl-dU-CE Phosphoramidite	0.25grams	6035	glen research
10-1051-90	O4-Triazolyl-dU-CE Phosphoramidite	100µmoles	2295	glen research
10-1052-02	4-Thio-dU-CE Phosphoramidite	0.25grams	11475	glen research
10-1052-90	4-Thio-dU-CE Phosphoramidite	100µmoles	5015	glen research
10-1052-95	4-Thio-dU-CE Phosphoramidite	50µmoles	2805	glen research
10-1053-02	5-OH-dU-CE Phosphoramidite	0.25grams	11475	glen research
10-1053-90	5-OH-dU-CE Phosphoramidite	100µmoles	3825	glen research
10-1054-02	pdU-CE Phosphoramidite	0.25grams	3315	glen research
10-1054-05	pdU-CE Phosphoramidite	0.5grams	6630	glen research
10-1054-90	pdU-CE Phosphoramidite	100µmoles	1105	glen research
10-1055-02	2'-deoxypseudoU-CE Phosphoramidite	0.25grams	16575	glen research
10-1055-90	2'-deoxypseudoU-CE Phosphoramidite	100µmoles	6035	glen research
10-1055-95	2'-deoxypseudoU-CE Phosphoramidite	50µmoles	3017.5	glen research
10-1056-02	Fluorescein-dT Phosphoramidite	0.25grams	11475	glen research

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Glen Research 10-1001说明书

美国GRC公司：Glen Research Corp 创建于1987年，专注于为DNA和RNA寡核苷酸的化学合成，修饰，标记和纯化提供zui广泛的亚磷酰胺和固体支持物，现已有近三十年的历史，在低聚核苷酸及修饰、改性领域一直处于地位。

结构研究

GlenResearch 目录号：10-1001-xx

7-Deaza-dA-CE Phosphoramidite描述：7- Deaza -dA-CE亚磷酰胺

EXTINCTION DATA

DILUTION/COUPLING DATA

DILUTION/COUPLING DATA

7-Deaza-dA-CE Phosphoramidite
描述：7- Deaza -dA-CE亚磷酰胺