Enzyme Research 是一家拥有超过25年的酶研究的实验室，生产和开发多种用于基本凝血研究的多种酶和辅因子。在过去的十年Enzyme Research Laboratories为科学家参与止血和血栓形成的研究提供了宝贵支持。Enzyme Research通过不断追求产品的zui高品质，赢得了世界各地凝血研究实验室的信任。

Enzyme Research Laboratories为生物技术公司,制药行业、医院和大学的研究实验室提供用于的纯化抗凝因子。除了其制造能力，Enzyme Research Laboratories也创新研发领域中的血液凝固技术。

Human Factor αXIIa

HFXIIa 1212a             Human Factor αXIIa 
                              （Activated Hageman Factor）

Human Factor α-XIIa is a serine protease responsible for the activation of Factor XI to XIa in the contact activation system. Human Factor XII and prekallikrein are thought to be involved in a reciprocal activation mechanism in which Factor XIIa activates prekallikrein to kallikrein, which in turn converts Factor XII to XIIa. Factor XIIa activates Factor XI to XIa thereby triggering the Contact Factor cascade. ERL offers Factor α-XIIa which is activated by the autoactivation process with Dextran Sulfate and re-purified to remove the activator. The protein purity is determined by SDS-PAGE and activity is determined via clotting assay.

Buffer composition = 4 mM Sodium Acetate-HCl/0.15 M NaCl/pH 5.3
*Extinction Coefficient （1%） = 14.1
Molecular Weight = 80,000 daltons

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